EFFECTS OF OXYGEN INHALATION ON HEMODYNAM ICS IN CHRONIC THROMBOEMBOLIC PULMONARY-HYPERTENSION

Purpose: This study evaluates the haemodynamic effects of oxygen inhal ation on pulmonary artery pressure and pulmonary vascular resistance i n patients with chronic thromboembolic pulmonary hypertension. Method: In 47 patients with chronic thromboembolic pulmonary hypertension hae modynamic parameters were measured before and after oxygen inhalation. Results: In moderately severe and severe pulmonary hypertension oxyge n inhalation significantly reduced mean pulmonary artery pressure by a bout 11.1% and 4.6%, respectively. However, pulmonary vascular resista nce was not significantly affected. Oxygen saturation improved and hea rt rate was reduced. Cardiac index decreased in severe pulmonary hyper tension. Systemic vascular resistance increased. Conclusion: We conclu de that oxygen inhalation reduces pulmonary artery pressure and improv es oxygen supply in patients with moderately severe and severe chronic thromboembolic pulmonary hypertension.