ACETYL CHLORIDE-METHANOL AS A CONVENIENT REAGENT FOR - A) QUANTITATIVE FORMATION OF AMINE HYDROCHLORIDES B) CARBOXYLATE ESTER FORMATION C) MILD REMOVAL OF N-T-BOC-PROTECTIVE GROUP
A. Nudelman et al., ACETYL CHLORIDE-METHANOL AS A CONVENIENT REAGENT FOR - A) QUANTITATIVE FORMATION OF AMINE HYDROCHLORIDES B) CARBOXYLATE ESTER FORMATION C) MILD REMOVAL OF N-T-BOC-PROTECTIVE GROUP, Synthetic communications, 28(3), 1998, pp. 471-474
Hydrogen chloride quatitativaly generated in situ by the addition of a
cetyl chloride to alcoholic solutions is a useful reagent for carboxyl
ic acid esterification, N-t-Boc deprotection and phosphoramide solvoly
sis reactions.