Background: Rheumatic symptoms were commonly described among soldiers
who served in previous wars. Objective: To describe the frequency of r
heumatology consultations, along with the diagnoses, and abnormal resu
lts on serologic testing in Gulf War veterans evaluated for Gulf War s
yndrome. Methods: The medical records of the first 250 consecutive Gul
f War veterans referred to the comprehensive clinical evaluation progr
am at Wilford Hall Air Force Medical Center and Brooke Army Medical Ce
nter, San Antonio, Tex, were reviewed for demographic characteristics
and frequency of subspecialty consultations. A retrospective review of
rheumatic diagnoses and the frequency of abnormal serologic test resu
lts was recorded. Results: Of the 250 Gulf War veterans evaluated in t
he comprehensive clinical evaluation program, 139 (56%) were referred
for rheumatology consultation, which was the most common elective subs
pecialty referral. Of the patients evaluated, 82 (59%) had soft tissue
syndromes, 19 (14%) had rheumatic disease, and 38 (27%) had no rheuma
tic disease. The most common soft tissue syndromes were patellofemoral
syndrome (33 patients [25%]), mechanical low back pain (23 patients [
18%]), and fibromyalgia (22 patients [17%]). Of the 19 patients with r
heumatic disease, 10 had osteoarthritis, 2 had rheumatoid arthritis, 2
had gout, and 1 each had systemic lupus erythematosus, Behcet disease
, parvovirus arthritis, psoriatic arthritis, and hypothyroid arthropat
hy. Abnormal serologic test results were common among the Gulf War pat
ients regardless of the presence or absence of rheumatic disease. Conc
lusions: The rheumatic manifestations in Gulf War veterans are similar
to symptoms and diagnoses described in previous wars and are not uniq
ue to active duty soldiers. Overall, the results of serologic screenin
g were poor predictors of the presence of rheumatic disease.