The structure of the headpiece of the TraM protein was investigated in
different solvents. The very first 22 amino acids which alternate in
their hydrophilic and hydrophobic character formed a helical structure
in the presence of a membrane mimetic. In water alone the structure w
as flexible with a small amount of helicity according to circular dich
roism measurements, whereas a loop structure was observed in dimethyl
sulphoxide. (C) Munksgaard 1998.