ANGIODYSPLASIA AND VON-WILLEBRANDS-DISEAS E TYPE-2 REVEALED BY INTESTINAL BLEEDING

Authors
LEFRANCOIS C DUBUS L MAUREL J CHICHE L LAVERGNE JM BORELDERLON A
Citation
C. Lefrancois et al., ANGIODYSPLASIA AND VON-WILLEBRANDS-DISEAS E TYPE-2 REVEALED BY INTESTINAL BLEEDING, Annales francaises d'anesthesie et de reanimation, 16(8), 1997, pp. 978-981
Citations number
10
Categorie Soggetti
Anesthesiology
Journal title
Annales francaises d'anesthesie et de reanimation → ACNP
ISSN journal
07507658
Volume
16
Issue
8
Year of publication
1997
Pages
978 - 981
Database
ISI
SICI code
0750-7658(1997)16:8<978:AAVETR>2.0.ZU;2-N
Abstract
The authors report a case of a 76-year-old man, with not past history of abnormal bleeding, who suffered an acute, recurrent, intestinal hae morrhage from extensive angiodysplasia of the colon. Intestinal bleedi ng and angiodysplasia were associated with a von Willebrand's disease. Genetic analysis showed a point mutation in arginine 611 of the matur e von Willebrand's factor subunit (A1 loop) confirming a von Willebran d's disease type 2.