CATHODIC STRIPPING VOLTAMMETRY OF THE ANTIBACTERIAL DRUG (NITROFURANTOIN)

Citation
M. Khodari et al., CATHODIC STRIPPING VOLTAMMETRY OF THE ANTIBACTERIAL DRUG (NITROFURANTOIN), Analytical letters, 31(2), 1998, pp. 251-262
Citations number
20
Categorie Soggetti
Chemistry Analytical
Journal title
ISSN journal
00032719
Volume
31
Issue
2
Year of publication
1998
Pages
251 - 262
Database
ISI
SICI code
0003-2719(1998)31:2<251:CSVOTA>2.0.ZU;2-F
Abstract
Cathodic stripping voltammetry was used to determine the antibacterial drug Nitrofurantoin in phosphate buffer (pH 5.5). The adsorptive peak was observed at -0.173 V vs. Ag/AgCl. The peak response was character ized with respect to pH, preconcetration time, possible interferences, deposition potential, supporting electrolytes and other variables. Th e obtained results were analyzed and the statistical parameters were c alculated Also the method was applied to determine the mentioned lug i n pharmaceutical formulations and urine. The limit of detection was 1x 10(-9) mol dm(-3).