NUTRITIONAL-REQUIREMENTS FOR GROWTH OF UROPATHOGENIC ESCHERICHIA-COLIIN HUMAN URINE

Authors
HULL RA HULL SI
Citation
Ra. Hull et Si. Hull, NUTRITIONAL-REQUIREMENTS FOR GROWTH OF UROPATHOGENIC ESCHERICHIA-COLIIN HUMAN URINE, Infection and immunity, 65(5), 1997, pp. 1960-1961
Citations number
11
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
65
Issue
5
Year of publication
1997
Pages
1960 - 1961
Database
ISI
SICI code
0019-9567(1997)65:5<1960:NFGOUE>2.0.ZU;2-U
Abstract
Enrichment with D-cycloserine was used to identify Escherichia coli au xotrophic mutants that exhibited limited growth in human urine. Bacter ial synthesis of guanine, arginine, and glutamine was found to be requ ired for optimal growth in urine, Mutants that required leucine, methi onine, serine, phenylalanine, or proline also exhibited reduced growth in urine, Several other nutritional mutants, including nicotinamide a uxotrophs, which are found frequently among cystitis isolates, exhibit ed normal growth in urine.