CEREBRAL METASTASIS IN PATIENTS WITH UTERINE CERVICAL-CANCER

We report on eight patients who developed brain metastases following u terine cervical cancer. The mean interval between diagnosis of the pri mary cancer and diagnosis of the brain metastasis was 28.4 months (ran ge: 6.1-61.8 months). Nausea and vomiting due to increased intracrania l pressure were the most frequent symptoms. Surgical excision of the b rain lesions, followed by postoperative radiotherapy, was performed in three patients. The other five patients received only cranial radioth erapy. When the metastatic brain lesions were detected, other distant metastatic lesions were confirmed at the same time in five patients. T he median survival time after diagnosis of the brain metastases was on ly 3.0 months.