A NEW STRONG INHIBITOR OF BETA-MANNOSIDASE

Authors
THERISOD H LETOURNEUX Y THERISOD M
Citation
H. Therisod et al., A NEW STRONG INHIBITOR OF BETA-MANNOSIDASE, Bioorganic & medicinal chemistry letters, 8(4), 1998, pp. 371-372
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
4
Year of publication
1998
Pages
371 - 372
Database
ISI
SICI code
0960-894X(1998)8:4<371:ANSIOB>2.0.ZU;2-7
Abstract
N-phenyl-carbamate of D-mannonohydroxymolactone (I) was synthesized fr om mannose and was shown to be the best competitive inhibitor of beta- mannosidase so far reported (K-i = 25 nM). (C) 1998 Elsevier Science L td. All rights reserved.