ACUTE NEUTROPENIA DECREASES INFLAMMATION ASSOCIATED WITH MURINE VAGINAL CANDIDIASIS BUT HAS NO EFFECT ON THE COURSE OF INFECTION

Authors
BLACK CA EYERS FM RUSSELL A DUNKLEY ML CLANCY RL BEAGLEY KW
Citation
Ca. Black et al., ACUTE NEUTROPENIA DECREASES INFLAMMATION ASSOCIATED WITH MURINE VAGINAL CANDIDIASIS BUT HAS NO EFFECT ON THE COURSE OF INFECTION, Infection and immunity, 66(3), 1998, pp. 1273-1275
Citations number
16
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
66
Issue
3
Year of publication
1998
Pages
1273 - 1275
Database
ISI
SICI code
0019-9567(1998)66:3<1273:ANDIAW>2.0.ZU;2-9
Abstract
We have used a mouse model of vaginal candidiasis to determine the eff ect of neutrophil depletion on (a) the clearance of Candida albicans a nd (b) the degree of inflammation associated with infection. No differ ences in recoverable yeast number or rate of clearance were observed b etween normal and neutrophil-depleted mice; however, vaginal inflammat ion was significantly decreased in neutrophil-depleted animals.