Za. Karcioglu et al., EXTRUSION OF POROUS POLYETHYLENE ORBITAL IMPLANT IN RECURRENT RETINOBLASTOMA, Ophthalmic plastic and reconstructive surgery, 14(1), 1998, pp. 37-44
High-density porous polyethylene allografts are used as orbital implan
ts in reconstruction of anophthalmic sockets. The use of this material
for integrated buried implants is rather new, and studies on removed
implants from humans are limited. We studied the case of a 6-year-old
boy with an extruded porous polyethylene implant due to orbital recurr
ence of retinoblastoma. The clinical and morphological features are re
ported. Histopathology revealed fibrovascular downgrowth in the outer
two thirds of the sphere. Scanning electron microscopy, however, docum
ented further downgrowth of fibrous tissue into the central core. Tran
smission electron microscopy depicted a spectrum of collagen fiber ori
entations to polyethylene material, ranging from perpendicular to conc
entric. Immunohistochemistry studies were inconclusive.