GRANULOMATOUS SLACK SKIN

A 48 year old women developed granulomatous slack skin (GSS), one of t he special forms of cutaneous T-cell lymphoma. The lesional skin slack with an atrophic, poikilodermic surface and granulomatous induration. Histopathological findings included epidermotropism, diffuse lymphoid cell infiltration and foreign body giant cells as well as granulomato us reactions from superficial to deep dermis, including part the subcu tis. The diagnosis was established by positive results for rearrangeme nt of the T-cell receptor gene. The therapeutic possibilities, especia lly with corticosteroides and monitoring the disease course by followi ng serum angiotensin converting enzyme activity are discussed.