SCREENING FOR COLORECTAL-CANCER PREDISPOS ITION

In the last years the advantages in molecular biology have developed a variety of useful tests in order to detect genetic mutations. These m utations are associated to a susceptibility of suffering a colo-rectal cancer. The genetic tests are designed to screen the disease although many problems can emerge when they are offered to the population. In this article, we will try to analize the advantages, disadvantages and the present indications for genetic testing in colo-rectal cancer, pa rticularity in cases of familial adenomatous polyposis and nonpolyposi s inherited colon cancer.