NITIDON, A NEW BIOACTIVE METABOLITE FROM THE BASIDIOMYCETE JUNGHUHNIA-NITIDA (PERS., FR.) RYV

Citation
A. Gehrt et al., NITIDON, A NEW BIOACTIVE METABOLITE FROM THE BASIDIOMYCETE JUNGHUHNIA-NITIDA (PERS., FR.) RYV, Zeitschrift fur Naturforschung. C, A journal of biosciences, 53(1-2), 1998, pp. 89-92
Citations number
15
Categorie Soggetti
Biology,Biology
ISSN journal
09395075
Volume
53
Issue
1-2
Year of publication
1998
Pages
89 - 92
Database
ISI
SICI code
0939-5075(1998)53:1-2<89:NANBMF>2.0.ZU;2-R
Abstract
Nitidon, a highly oxidised pyranone derivative produced by the basidio mycete Junghuhnia nitida, has been isolated and its biological activit ies evaluated. The structure was determined by spectroscopic methods. Nitidon exhibits antibiotic and cytotoxic activities and induces morph ological and physiological differentiation of tumor cells at nanomolar concentrations.