Between 1977 and 1996 we treated 176 patients suffering from complicat
ed urethral strictures with the mesh-graft urethroplasty. This operati
on technique has replaced the Bengt-Johanson-Operation which had been
used frequently until that date. The Cecil-Operation has been totally
abandoned, because in our opinion the usage of scrotal skin in urethra
l reconstruction is obsolete today. The mesh-graft technique is based
on the free transfer of meshed prepuce (full-thickness skin or split-t
hickness skin) in a two stage procedure. In 37 patients the inner laye
r of the prepuce was used, in 63 patients we only used split-thickness
skin grafts and in 76 patients we applied a combination of both, the
inner layer of the prepuce in addition to a split-thickness skin graft
. After complete healing of the graft (first stage) the formation of t
he neourethra follows as the second stage procedure. The mesh graft pr
ocedure can be used to treat all kinds of strictures independant of th
e etiology or localisation. Hair growth, diverticula development and s
tone formation that are observed frequently as complications with scro
tal skin substitutes can be avoided. Due to these advantages encouragi
ng long term results could be obtained with the mesh graft urethroplas
ty. In 162 patients (92 %) with a minimum follow-up of 7 years we achi
eved a successful result of the operations, a significant improvement
could be obtained in 7 patients (4 %). Unfortunately in further 7 case
s (4 %) the operation method ultimately failed. In particular in patie
nts with complicated and severe strictures after numerous unsuccessful
l prior reconstructive attempts, extensive long strictures and strictu
res in paraplegic patients, mesh graft;urethroplasty has been shown to
be a safe and reliable treatment option.