Palliative therapies for advanced oesophageal cancer include surgery,
radiation therapy, chemotherapy, endoscopic procedures and combination
s of these. Of the non-endoscopic modalities is external beam radiatio
n therapy (EBRT) effective and non-invasive. A disadvantage is that re
lief of dysphagia only occurs over a period of 4-6 weeks. Brachytherap
y is more rapid in locally controlling tumour growth and in relieving
dysphagia. One of the more commonly used endoscopic procedures is lase
r therapy, which provides symptomatic relief with low complication rat
es. Recurrent dysphagia is a problem necessitating repeated treatment
sessions. Self-expanding metal stents offer a high degree of palliatio
n and are associated with fewer complications compared with prosthetic
tubes. Longer palliation and perhaps even longer survival might be ac
hieved by the combination of different therapies. Most promising are t
he combination of EBRT plus brachytherapy or chemoradiation. Now is th
e time to determine which treatment (combination) is best for individu
al patients.