A CASE OF CANINE CENTRAL-NERVOUS-SYSTEM CRYPTOCOCCOSIS - MANAGEMENT WITH FLUCONAZOLE

Authors
TICHES D VITE CH DAYRELLHART B STEINBERG SA GROSS S LEXA F
Citation
D. Tiches et al., A CASE OF CANINE CENTRAL-NERVOUS-SYSTEM CRYPTOCOCCOSIS - MANAGEMENT WITH FLUCONAZOLE, The Journal of the American Animal Hospital Association, 34(2), 1998, pp. 145-151
Citations number
25
Categorie Soggetti
Veterinary Sciences
Journal title
The Journal of the American Animal Hospital Association → ACNP
ISSN journal
05872871
Volume
34
Issue
2
Year of publication
1998
Pages
145 - 151
Database
ISI
SICI code
0587-2871(1998)34:2<145:ACOCCC>2.0.ZU;2-X
Abstract
A three-year-old, female Labrador retriever was presented for acute ge neralized seizures. Disseminated cryptococcosis with central nervous s ystem (CNS) involvement was diagnosed by serum and cerebrospinal fluid (CSF) fungal titers, histopathological examination, and magnetic reso nance imaging (MRI). Fluconazole therapy resulted in prolonged, substa ntial clinical improvement for a period of one year. This report docum ents the diagnosis of a case of cryptococcal meningoencephalitis and i ts management with the new antifungal agent, fluconazole.