Along with the rapid biomedical development of prenatal screening test
s, target groups' attitudes and decisionmaking about, and the acceptan
ce of, screening procedures have come into focus. To understand users
decision-making, it is essential to understand users' knowledge and pe
rceptions of a procedure. The aim of this study was to examine Finnish
women's knowledge and perceptions of, and stated reasons to participa
te in, two prenatal screening tests: serum screening and mid-trimester
ultrasound screening. Subjects (n=1035) for the serum screening surve
y were catered for in the maternity care centres of two Finnish towns,
where serum screening is available for all pregnant women. After one
reminder, 88 per cent returned the questionnaire. Subjects (n=497) for
the mid-trimester ultrasound screening survey were catered for in the
obstetrical and gynaecological outpatient clinic of the city hospital
of another town; the response rate was 85 per cent. Women's perceptio
ns of the studied prenatal screening tests, serum screening and mid-tr
imester ultrasound screening, differed significantly, even though both
are used to detect fetal malformations. Serum screening was far more
often perceived to be connected with finding diseases or abnormalities
than ultrasound screening. Another interesting finding was that the s
tated reasons for screening in general and the subjective reasons for
participation were different. Reassurance was the personal reason most
often mentioned in both the serum screening and the ultrasound group.
Almost all women had the most superficial knowledge about serum scree
ning; they knew whether it had been offered and that it is done to scr
een for Down syndrome. The greatest gaps in knowledge concerned the se
nsitivity of serum screening, its use in screening for congenital neph
rosis, and diagnostic tests and their risks. Knowledge was poorer amon
g women without a high school education. When counselling women about
prenatal screening tests, more emphasis should be given to the sensiti
vity of serum screening, all of its screening uses, and the possible d
iagnostic tests and their risks. The fact that ultrasound screening ca
n detect conditions which may lead to the possibility of a selective a
bortion should also be explained more fully. (C) 1998 John Wiley &z So
ns, Ltd.