CASE-REPORT - CEREBELLAR HEMI-HYPOPLASIA

Cerebellar hypoplasia is a prominent feature of fetal brain pathology. The lesion is rarely isolated or asymmetric. Various aetiological fac tors have been proposed. The frequency of cerebellar hypoplasia as a c ongenital defect in humans is unknown. A single case is described of u nilateral cerebellar hypoplasia with intact vermis that was detected o n prenatal ultrasound examination. Changes in the appearance of the ab normality over the course of the pregnancy raised the possibility of a disruptive vascular aetiology with destruction of normally formed str uctures. Prenatal ultrasound, post-delivery cranial ultrasound, and MR I images are presented to support the hypothesis. (C) 1998 John Wiley & Sons, Ltd.