COMPLETE HEART-BLOCK IN ASSOCIATION WITH GRAFT-VERSUS-HOST DISEASE

An infant who received haploidentical BM for severe combined immunodef iciency (SCID) developed acute, reversible complete heart block in ass ociation with an exacerbation of GVHD, Respiratory distress and myocar dial dysfunction were also seen with this and previous GVHD exacerbati ons, The patient had not received chemotherapy or radiation prior to B MT, The complete heart block resolved after 1 week of intensive immuno suppression. The association of complete heart block with GVHD is impo rtant because the heart block is potentially reversible with prompt, a ggressive control of the GVHD.