CAVERNOUS ANGIOMAS OF THE BRAIN-STEM IN CHILDREN

Out of 27 children with intracranial cavernous angiomas observed in a 17-year period of time, 3 presented with their lesion located in the b rain stem. A further 19 pediatric cases of brain stem cavernous angiom as sufficiently well described for a reliable analysis were collected from the literature and evaluated for the present study. The widesprea d use of MR imaging has significantly increased the possibility of rec ognizing brain stem cavernomas at an early age indeed, their incidence is nowadays regarded to range between 9 and 15% of pediatric cavernou s angiomas. A female predominance was noted in the present study. Foca l neurological deficits are the most frequent presenting symptoms; the y tend to occur acutely in most cases, although subsequent improvement may then be observed in several patients. Recurrent hemorrhages from the angioma result usually in heavier neurological signs. Surgical app roaches have to be planned according to the location of the lesion, an d to the site where the angioma is eventually in contact with the pial or ependymal surface. No surgical deaths were observed in these 22 ch ildren; only 2 patients presented a mild persistent worsening of their neurological status after the operation. These good results indicate that brain stem cavernous angiomas are actually a surgical lesion in s pite of their apparently unfavorable location, The good prognosis is r elated to the anatomophysiological features of these lesions, which us ually displace the brain stem structures rather than invade them, and are characterized by a low-pressure and slow blood flow circle.