Sa. Hassarajani et Vr. Mamdapur, A 3 STEP SYNTHESIS OF 11-CYCLOHEPTYLUNDECANOIC ACID, A COMPONENT OF THE THERMOACIDOPHILE ALICYCLOBACILLUS-CYCLOHEPTANICUS, Molecules, 3(2), 1998, pp. 41-43
A simple synthesis of the methyl ester of 11-cycloheptylundecanoic aci
d (1), isolated from the lipid fraction of the thermoacidofile, Alicyc
lobacillus cycloheptanicus has been developed. This involved regiosele
ctive Grignard coupling between cycloheptylmagnesium bromide and methy
l 11-bromoundecanoate (2), prepared from 10-undecanoic acid.