To assess the severity and nature of symptoms of psychiatric distress
among tertiary center epilepsy patients, we administered the Brief Sym
ptom Inventory (BSI) and Center for Epidemiologic Studies-Depression S
cale (CES-D) to adult patients evaluated at our tertiary center who we
re diagnosed with Epilepsy (EPI; n = 37), or Chronic Lyme Disease (CLD
, n = 38). We compared results in these groups to published studies in
normal healthy adults (NHA) and psychiatric outpatients (Psych). Mean
global BSI and CES-D scares were both markedly elevated in the EPI an
d CLD groups compared to NHA but less than Psych. Subscores of the BSI
varied among the EPI and CLD,stoups with higher obsessive compulsive
symptoms among CLD patients (p=.014), higher paranoid symptoms in the
EPI group (p=.021), and a trend toward higher somatization subscores i
n the CLD group (p=.054). Symptoms of psychiatric distress including d
epression are common among tertiary epilepsy tenter patients as well a
s patients with CLD.