Background: Little is known of colonic lipomas, especially in an Asian
population, and their management is controversial. Methods: A compute
rized colonoscopy database was analysed and patients with colonic lipo
mas were reviewed. Results: There were 16 colonic lipomas (incidence o
f 0.15%) in a series of 10 658 consecutive colonoscopies. There were s
even men and nine women, with a mean age of 61.8 years (range: 28-80 y
ears). The size of the lipomas ranged from 1.5 to 6 cm; all those larg
er than 3.5 cm were symptomatic (P = 0.05). The most common symptom wa
s mild bleeding per rectum. Right-sided lipomas were palpable while le
ft-sided lipomas presented with obstructive symptoms. Colonoscopic rem
oval by hot biopsy or snare polypectomy was possible where the lipomas
were 2.5 cm and pedunculated. Surgery was performed in six patients (
four open, two laparoscopic) for symptoms and to exclude malignancy. T
here was no morbidity or mortality. Conclusions: Small or pedunculated
lipomas may be safely removed colonoscopically and the diagnosis conf
irmed histologically. Larger lipomas require surgical resection for re
lief of symptoms or to exclude malignancy.