Jh. Hughes et al., PRIMARY INTRATHYROIDAL PARAGANGLIOMA WITH METACHRONOUS CAROTID-BODY TUMOR - REPORT OF A CASE AND REVIEW OF THE LITERATURE, Pathology research and practice, 193(11-12), 1997, pp. 791-796
A case of primary intrathyroidal para ganglioma is reported, and the l
ight microscopic and immunohistochemical findings are described. Prima
ry paragangliomas of the thyroid region are extremely uncommon and are
therefore often confused clinically and histopathologically with more
common intrathyroidal mass lesions. The diagnostic difficulties are u
nderscored by the present case, which was misdiagnosed twice, firstly
as a medullary thyroid carcinoma and secondly as a follicular thyroid
carcinoma. Immunohistochemistry may be very helpful in arriving at the
correct diagnosis. The case was further complicated by a second neck
mass contralateral to the original thyroid nodule, which was interpret
ed as consistent with metastasis. The second lesions was proved angiog
raphically and histologically to be a carotid body paraganglioma.