Noncompliance is a common problem in patients with end-stage renal dis
ease. In this study, we assessed the relationship between knowledge of
disease and dietary compliance in a cohort of 56 dialysis patients. B
ased on a health belief model of adherence, we predicted that dialysis
patients who knew more about kidney disease and its treatment would b
e more compliant than those who knew less about these matters. We also
examined the relationship between dietary compliance and patients' em
otional well-being. We used a composite measure of compliance consisti
ng of serum K, P, and interdialytic weight gain. A 30-item ''Kidney Di
sease Questionnaire'' was used to assess patients' knowledge of their
illness. Contrary to prediction, compliers did not score higher on the
knowledge questionnaire; in fact, the observed correlation of .32 was
in the opposite direction. In the same vein, we found no relationship
between compliance and emotional well-being. These results, although
somewhat surprising, add to a growing body of research which indicates
that medical compliance involves more than educating patients about t
he mechanisms and treatment of their illness.