G. Fountzilas et al., PROGNOSTIC VARIABLES IN CREEK PATIENTS WITH STAGE-II BREAST-CANCER - A HELLENIC COOPERATIVE ONCOLOGY GROUP-STUDY, Anticancer research, 17(6D), 1997, pp. 4681-4689
The independent effects of several patient, tumor and treatment-relate
d prognostic factors on relapse-free survival (RFS) and overall surviv
al (OS) were assessed by Cox multivariate regression analysis in 988 G
reek patients with stage II breast cancer. At a median follow-up time
of 83 (range 3.3-131+) months and after the evaluation of all patients
together; the number of positive axillary nodes (p<0.0001), tumor siz
e (p = 0.0024) and tumor grade (p=0.0008) were identified as significa
nt prognostic factors for RFS. Also, the number of positive nodes (p<0
.0001), tumor size (p=0.0002) and ER status (p=0.0001) were found to b
e significant for OS. These short-term prognostic variables are simila
r to those reported for this group of patients in other European count
ries and in the USA.