Hypoprothrombinemic states are commonly treated with injectable vitami
n K. Cutaneous vitamin K hypersensitivity can manifest as eczematous o
r sclerodermoid lesions and historically has been related to the use o
f fat-soluble vitamin K1. We present a case of warfarin-induced hypopr
othrombinemia treated with aqueous vitamin K1, which resulted in the a
ppearance of eczematous vitamin K1 hypersensitivity.