Although drug eruptions caused by pravastatin and other lovastatin ana
logs have previously been described, reports of lichenoid eruptions ar
e rare. We report a patient whose lichenoid lesions developed after in
itiation, resolved on discontinuation, and reappeared on rechallenge w
ith pravastatin therapy. A brief review of lichenoid drug eruptions an
d skin lesions due to 3-hydroxy-3-methylglutaryl coenzyme A reductase
inhibitors is discussed.