AN UNUSUAL ERYTHROLIDE CONTAINING A BICYCLE[9.2.1.]TETRADECANE SKELETON

Authors
BANJOO D MAXWELL AR MOOTOO BS LOUGH AJ MCLEAN S REYNOLDS WF
Citation
D. Banjoo et al., AN UNUSUAL ERYTHROLIDE CONTAINING A BICYCLE[9.2.1.]TETRADECANE SKELETON, Tetrahedron letters, 39(12), 1998, pp. 1469-1472
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
12
Year of publication
1998
Pages
1469 - 1472
Database
ISI
SICI code
0040-4039(1998)39:12<1469:AUECAB>2.0.ZU;2-C
Abstract
Erythrolide K (4), isolated from Erythropodium caribaeorum possesses a n unusual bicycle [9.2.1.] tetradecane skeleton. The structure was ded uced by 2D NMR and confirmed by X-ray analysis. It was synthesised in two steps from erythrolide A (2), the first involving a thermal [1,5] sigmatropic hydrogen shift to give the intermediate (3). (C) 1998 Else vier Science Ltd. All rights reserved.