ZIRCONIUM AND HAFNIUM CATIONS RAPIDLY CLEAVE MODEL PHOSPHODIESTERS INACIDIC AQUEOUS-SOLUTIONS

Authors
MOSS RA ZHANG J RAGUNATHAN KG
Citation
Ra. Moss et al., ZIRCONIUM AND HAFNIUM CATIONS RAPIDLY CLEAVE MODEL PHOSPHODIESTERS INACIDIC AQUEOUS-SOLUTIONS, Tetrahedron letters, 39(12), 1998, pp. 1529-1532
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
12
Year of publication
1998
Pages
1529 - 1532
Database
ISI
SICI code
0040-4039(1998)39:12<1529:ZAHCRC>2.0.ZU;2-Z
Abstract
Aqueous solutions of 20-fold excess Zr4+ and Hf4+ at pH 3.5 (37 degree s C) hydrolyze phosphodiester substrates 1-3 very rapidly. The reactiv ity of Zr4+ (with rate constants up to 0.015 s(-1) for 2 at 1 mM Zr4+) exceeds that of most other transition metal cations. (C) 1998 Elsevie r Science Ltd. All rights reserved.