Migraine imposes substantial burdens both on individual headache suffe
rers and on society. Prevalence studies reveal that the condition affe
cts about 18% of women and about 6% of men. Prevalence is highest betw
een the ages of 25 and 55, during the peak productive-years; Despite t
he development of new and effective treatment options, migraine remain
s an underdiagnosed and undertreated condition. In this article, we re
view the incidence, prevalence. and distribution of migraine and the c
onditions which are comorbid with migraine. (C) 1998 Wiley-Liss, Inc.