BIOCOMPATIBILITY OF PRIMER, ADHESIVE AND RESIN COMPOSITE SYSTEMS ON NON-EXPOSED AND EXPOSED PULPS OF NONHUMAN PRIMATE TEETH

Purpose: To evaluate the histologic response of 332 non-exposed and 12 7 exposed monkey pulps applying nine adhesive systems. Materials and M ethods: Class V and Class I cavities were used in non-exposed and expo sed monkey pulps at the three ISO usage time intervals. Results: There were no histologic differences in pulp responses among the nine adhes ive systems used in either Class V and/or Class I cavities when compar ed to pulp responses of Ca(OH)(2) controls at the ISO time intervals. The nine adhesive systems and resin composites are non-toxic to either non-exposed or exposed pulps, being biologically compatible to pulp t issues when placed on mechanical pulp exposures following hemorrhage c ontrol with a 2.5% NaOCl and per manufacturers' directions. It is impe rative that clinicians understand the biological importance of hemorrh age control as well as the technique sensitivity of hydrophilic primer s in order to optimize the efficacy of adhesives for clinical success against microleakage of bacterial factors.