Sc. Stoner et al., ANTIDEPRESSANT OVERDOSES AND RESULTANT EMERGENCY DEPARTMENT SERVICES - THE IMPACT OF SSRIS, Psychopharmacology bulletin, 33(4), 1997, pp. 667-670
Suicide is a major source of morbidity and mortality in patients with
mental illness. The selective serotonin reuptake inhibitors (SSRIs) an
d other newer nontricyclic antidepressants appear to have less clinica
lly significant toxicity in overdose, resulting in lower costs of trea
tment when compared with tricyclic antidepressant (TCA) overdoses. The
resource utilization and cost of treatment for SSRI overdoses may not
be less if (1) these agents are commonly ingested with other potentia
lly toxic substances, or (2) health care practices have not changed in
response to the apparent greater safety of SSRIs. This study evaluate
s demographic variables of antidepressant overdoses to determine wheth
er differences exist in treatments and monitoring. Additionally, this
study evaluates costs associated with care and the impact of co-ingest
ants on those same factors.