GENE INDUCTION IN INTESTINAL EPITHELIAL-CELLS IN RESPONSE TO INJURY

Authors
STENSON WF ALPERS DH
Citation
Wf. Stenson et Dh. Alpers, GENE INDUCTION IN INTESTINAL EPITHELIAL-CELLS IN RESPONSE TO INJURY, Current opinion in gastroenterology, 14(2), 1998, pp. 83-89
Citations number
35
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Current opinion in gastroenterology → ACNP
ISSN journal
02671379
Volume
14
Issue
2
Year of publication
1998
Pages
83 - 89
Database
ISI
SICI code
0267-1379(1998)14:2<83:GIIIEI>2.0.ZU;2-M
Abstract
Intestinal epithelial cells in acute infections and in inflammatory bo wel disease express a series of genes that are not expressed in health . Among these genes are those for interleukin-8, cyclooxygenase-2, and inducible nitric oxide synthase. The mechanisms by which these genes are induced in infection or in inflammatory bower disease are not know n, although many of the induced genes have an NF-kappa B site in their promoters.