Md. Mccoll et al., RESPIRATORY SYNCYTIAL VIRUS-INFECTION IN ADULT BMT RECIPIENTS - EFFECTIVE THERAPY WITH SHORT-DURATION NEBULIZED RIBAVIRIN, Bone marrow transplantation, 21(4), 1998, pp. 423-425
Respiratory syncytial virus (RSV), a common cause of both upper and lo
wer respiratory tract infection (LRTI) in infants and children, is rar
ely described as an infective agent in adults. It has been reported in
bone marrow transplant (BMT) recipients and patients with malignancy
immunosuppressed by chemotherapy. Such reports are often associated wi
th a high mortality. We report an outbreak of RSV infection which occu
rred predominantly in BMT recipients in which early investigation and
institution of ribavirin therapy resulted in all patients making a ful
l recovery.