Acromegaly is recognized as a cause of difficulty in airway management
and intubation. We evaluated prospectively the conditions for laryngo
scopy and fibreoptic intubation in 15 acromegalic patients. Each patie
nt served as his or her own control. Ventilation of the lungs with a f
ace mask was successful in all patients. In five of 15 patients the vo
cal cords could not be seen using the Macintosh laryngoscope with a si
ze 5 blade. Difficult laryngoscopy was associated significantly with t
he number of attempts required to see the vocal cords with the fibresc
ope (P<0.01, Spearman rank correlation). The larynx could not be seen
with both techniques in one patient, and the trachea was intubated bli
ndly with the help of an introducer. Our results showed that fibreopti
c intubation may prove difficult or fail in acromegalic patients. Diff
iculties in seeing the vocal cords with a fibrescope were present most
often in patients who also had probable intubation difficulties with
a rigid laryngoscope.