SUCCESSFUL TREATMENT OF GROVERS-DISEASE WITH CALCIPOTRIOL

We report the case of an 84-year-old man with clinical, histological a nd electron-microscopic features of a Darier-like pattern of Grover's disease. The lesions had a persistent course, with a 5-month history b efore diagnosis and a clinical onset 2 years after the surgical remova l of a cholangiocarcinoma. A significant clinical improvement was obse rved after a three-week course of calcipotriol ointment applied as a m onotherapy regimen. Clinical uses of topical calcipotriol in dermatolo gical conditions are reviewed with emphasis on dyskeratotic disorders.