THE DEDUCED PRIMARY STRUCTURE OF A RIBOSOMAL-PROTEIN S4 FROM TRYPANOSOMA-CRUZI

Two cDNA clones encoding a protein homologous to ribosomal protein S4 from the protozoan parasite Trypanosoma cruzi were isolated and charac terized. Both clones potentially encode for an identical basic protein of 273 amino acids. Sequence comparisons with other species indicate that this protein is highly conserved. Hybridization studies are consi stent with the occurrence of two genes in T. cruzi encoding this ribos omal protein. An RNA of approximately 1 kb was present in both exponen tially growing and stationary phase derived epimastigotes, and no sign ificant differences were detected in its steady state concentration. ( C) 1998 Elsevier Science B.V.