SEGREGATION ANALYSIS OF ANIMAL PEDIGREE DATA FROM INTER-POPULATION CROSSES

The general method of segregation analysis of pedigree data has been d eveloped and widely used in human genetics. We modified this method to examine pedigree data coming from inter-population crosses. These kin ds of pedigrees are common in laboratory and farm animal breeding. Thi s paper describes a rationale for the method and illustrates its appli cation to the study of inheritance of litter size and of male sterilit y in hybrid stock of the house musk shrew (Suncus murinus) derived fro m crosses of two geographically isolated populations.