The aim of the work is to describe briefly the methodology for establi
shing and operating an internal dosimetry program in a complex waste p
rocessing facility, with special emphasis to the complexity of activit
ies and problems and to the uncertainties in attributing doses from bi
oassay data. The purpose is not to make a fundamental study of the dos
imetric models as such, but to give the viewpoint of the practical hea
lth physicist who is confronted with interpretation problems as the co
nsequence of an intake of radionuclides. Some model parameters are dis
cussed in relation to acute or chronic intakes. A practical contaminat
ion case is elaborated.