We report the case of a patient admitted to the hospital with psychiat
ric troubles. Soon after admission, he presented severe hepatitis of u
nknown origin, Careful review of the charts, transvenous liver biopsy,
right heart and hepatic pressure measurements, negative toxicologic a
nd viral screenings were highly suggestive of hypoxic hepatitis, Indee
d, the patient had previously been treated for a decompensated cardiom
yopathy and medications stopped prior to the current admission, Withou
t clear clinical evidence of heart failure he presented a brief malais
e two days before the increase in liver enzymes, Hotter heart recordin
g showed afterwards bouts of ventricular tachycardia. Treatment with D
obutamine and antiarrythmics led to a rapid decrease of transaminase l
evels and recovery in liver function, Unfortunately, he died three wee
ks later from his cardiomyopathy. This case illustrates the need for c
ardiovascular work-up in the context of hepatitis from unknown origin.