Gs. Nunes et al., ANALYSIS OF PESTICIDES IN FOOD AND ENVIRONMENTAL-SAMPLES BY ENZYME-LINKED IMMUNOSORBENT ASSAYS, TrAC. Trends in analytical chemistry, 17(2), 1998, pp. 79-87
Enzyme-linked immunosorbent assays (ELISAs) are the most extensively s
tudied types of immunoassay and their application in pesticide residue
monitoring is an area with enormous potential for growth. In comparis
on with classical analytical methods, ELISA methods offer the possibil
ity of highly sensitive, relatively rapid, and cost-effective measurem
ents. This review introduces the general ELISA formats used, focusing
on their use in pesticide analysis. Identifying and studying the effec
ts of interferences in immunoassays is an active area of research and
we discuss the matrix effects observed in several studies involving e.
g. food, crop and environmental samples. The procedures to eliminate t
he matrix interferences are briefly discussed. (C) 1998 Elsevier Scien
ce B.V.