EXTRACTIVES FROM ZANTHOXYLUM-LEMAIRIE ROOT AND STEM

Chemical investigations by chromatography and CC-MS analyses of the ro ot and stem extracts of Zanthoxylum lemairie resulted in the detection and isolation of nine aliphatic and aromatic amides, four alkaloids, five coumarins and ten lignans. The structure of some constituents wer e confirmed by synthesis and in particular the lignan structures were elucidated by extensive spectroscopic methods. The isolation of a carb azole alkaloid and the accumulation of a large number of lignans by Z. lemairie is of chemotaxonomic and biogenetic significance. This is th e first report of glycozoline,piperlonguminine and six lignans in the genus Zanthoxylum.