SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF 3-SUBSTITUTED 1H-INDOLE [3,2-D]-1,2,3-TRIAZIN-4 (3H)-ONES

Authors
GARUTI L ROBERTI M ROSSI T CASTELLI M MALAGOLI M
Citation
L. Garuti et al., SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF 3-SUBSTITUTED 1H-INDOLE [3,2-D]-1,2,3-TRIAZIN-4 (3H)-ONES, European journal of medicinal chemistry, 33(1), 1998, pp. 43-46
Citations number
11
Categorie Soggetti
Chemistry Medicinal
Journal title
European journal of medicinal chemistry → ACNP
ISSN journal
02235234
Volume
33
Issue
1
Year of publication
1998
Pages
43 - 46
Database
ISI
SICI code
0223-5234(1998)33:1<43:SAAAO3>2.0.ZU;2-3
Abstract
Some 3-substituted indole-triazin-4-ones were synthesized. Their antip roliferative activity against chronic myeloid leukaemia and non-Hodgki n lymphoma human cells was compared in vitro with that of daunorubicin . One compound appeared to be very effective against human CML. (C) El sevier, Paris.