Purpose. To describe a new manifestation of Peters' anomaly. Methods.
We managed four infants with an unusual form of Peters' anomaly. One e
ye of each patient had a thickened and scarred cornea, mimicking a cor
neal staphyloma, protruding anteriorly from the corneal plane. The oth
er eye of each patient ranged from normal to having severe ocular anom
alies. A corneal transplant was performed in each case. Results. Follo
w-up ranged from 1 to 3 years. Three eyes maintained graft clarity for
at least 1 year. Each of these eyes developed vision. Two of these ey
es developed glaucoma. The one eye with graft failure developed an ino
perable retinal detachment. The histopathology of each corneal burton
showed changes consistent with Peters' anomaly. Conclusions. These cor
neas demonstrated characteristics of both Peters' anomaly and congenit
al anterior staphyloma. Despite their severe anomalies, surgery succes
sfully restored a more normal cosmetic appearance in all four eyes and
vision in three eyes.