The involvement of cytochrome P450 enzymes in many complex fungal bioc
onversion processes has been characterized in recent years, Accordingl
y, there is now considerable scientific interest in fungal cytochrome
P450 enzyme systems, In contrast to S. cerevisiae, where surprisingly
few P450 genes have been identified, biochemical data suggest that man
y fungi posses numerous P450 genes, This review summarizes the current
information pertaining to these fungal cytochrome P450 systems, with
emphasis on the molecular genetics, The use of molecular techniques to
improve cytochrome P450 activities in fungi is also discussed. (C) 19
98 Academic Press.