HISTOPATHOLOGICAL EVALUATION OF THE TISSUE-REACTIONS TO ENDO-FILL ROOT-CANAL SEALANT AND FILLING MATERIAL IN RATS

In this in vivo study, the tissue reactions to silicone-based Endo-Fil l root canal filling material were histopathologically evaluated, The reaction of rat connective tissue to polyethylene tube implants that w ere filled with Endo-Fill were evaluated at 2 days, and at 1, 2, 4, an d 8 weeks, Four tubes were implanted in each rat subcutaneously, and a total of 15 rats were used, Rats were killed, and the specimens were examined under the light microscope (x115 and x230), At the end of 8 w k, a thin fibrous wall with an almost completed advanced healing proce ss was observed around the implant material, but no capsule formation or any inflammatory infiltration was seen.