MULTINUCLEAR NMR CHARACTERIZATION OF THE COMPLEXES BETWEEN CHIRAL 3-AMINOPYRROLIDINE LITHIUM AMIDES AND N-BUTYLLITHIUM

Authors
PRIGENT Y CORRUBLE A VALNOT JY MADDALUNO J DUHAMEL P DAVOUST D
Citation
Y. Prigent et al., MULTINUCLEAR NMR CHARACTERIZATION OF THE COMPLEXES BETWEEN CHIRAL 3-AMINOPYRROLIDINE LITHIUM AMIDES AND N-BUTYLLITHIUM, Journal de chimie physique et de physico-chimie biologique, 95(2), 1998, pp. 401-405
Citations number
16
Categorie Soggetti
Biology,"Chemistry Physical
Journal title
Journal de chimie physique et de physico-chimie biologique → ACNP
Volume
95
Issue
2
Year of publication
1998
Pages
401 - 405
Database
ISI
SICI code
Abstract
From a set of one- and two-dimensional H-1, C-13 and Li-6 NMR experime nts, we propose the formation of a well organised 1:1 tight complex be tween substituted 3-aminopyrrolidine lithium amides and n-butyllithium . This complex is probably at the origin of the stereoselection observ ed in the asymmetric condensation of n-butyllithium onto aromatic alde hydes.