THE PRELIMINARY SOLUTION STRUCTURE OF HUMAN P8(MTCP1), A PROTEIN ENCODED BY THE PUTATIVE MTCP1 ONCOGENE

Authors
BARTHE P GUIGNARD L YANG YS CHICHE L STRUB MP HOH F STERN MH ROUMESTAND C
Citation
P. Barthe et al., THE PRELIMINARY SOLUTION STRUCTURE OF HUMAN P8(MTCP1), A PROTEIN ENCODED BY THE PUTATIVE MTCP1 ONCOGENE, Journal de chimie physique et de physico-chimie biologique, 95(2), 1998, pp. 447-453
Citations number
15
Categorie Soggetti
Biology,"Chemistry Physical
Journal title
Journal de chimie physique et de physico-chimie biologique → ACNP
Volume
95
Issue
2
Year of publication
1998
Pages
447 - 453
Database
ISI
SICI code
Abstract
The NMR solution structure of the cystein-rich human p8 protein coded by the oncogene MTCP1 reveals an original scaffold consisting of three alpha-helices, two of them tightly held together by two disulphide br idges in an antiparallel alpha-hairpin MTCP1 was found to be expressed in mature prolymphocytic leukemias.